Pharmacogenetics and Pharmacogenomics
Pharmacogenetics refers to however variation in one single gene influences the response to one drug and Pharmacogenomics refers to all of the genes (the genome) will influence responses to drugs. The general feature of those numerous lesions is that 2 nucleotides on opposite strands are joined covalently. Mutagenicity and carcinogenicity are clearly correlated. Understanding the specificity of mutagens in microorganisms leads to the direct implication of environmental mutagens in the cause of human cancers.
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